gene: tbb-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in axonemal microtubule. Expressed in HSN; accessory cell; epithelial cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Leber congenital amaurosis with early-onset deafness; complex cortical dysplasia with other brain malformations (multiple); and congenital symmetric circumferential skin creases 1. Is an ortholog of human TUBB4B (tubulin beta 4B class IVb).