gene: pde-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 3',5'-cyclic-GMP phosphodiesterase activity and cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Involved in several processes, including determination of adult lifespan; negative regulation of cGMP-mediated signaling; and response to alkaline pH. Expressed in AFDL and AFDR. Is an ortholog of human PDE10A (phosphodiesterase 10A).