- gene: shn-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ionotropic glutamate receptor binding activity and synaptic receptor adaptor activity. Involved in defecation and rhythmic behavior. Predicted to be located in dendritic spine; postsynaptic density; and postsynaptic membrane. Expressed in several structures, including amphid neurons; egg-laying apparatus; pharyngeal-intestinal valve; somatic nervous system; and sperm. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in Phelan-McDermid syndrome; autistic disorder; and schizophrenia 15. Is an ortholog of human SHANK1 (SH3 and multiple ankyrin repeat domains 1).
- sequence feature: WBsf717805
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=C33B4.3. Surounding gene organisation=divergent
- sequence feature: WBsf717804
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=C33B4.3. Surounding gene organisation=divergent
- sequence feature: WBsf717803
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=C33B4.3. Surounding gene organisation=divergent
- sequence feature: WBsf717806
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=C33B4.3. Surounding gene organisation=divergent
- sequence feature: WBsf717807
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=C33B4.3. Surounding gene organisation=divergent
- strain: VC376
Caenorhabditis elegans - strain: RB1196
Caenorhabditis elegans