gene: idh-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable isocitrate dehydrogenase (NADP+) activity. Predicted to be involved in NADP metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including D-2-hydroxyglutaric aciduria 2; gastrointestinal system cancer (multiple); and lung non-small cell carcinoma (multiple). Is an ortholog of human IDH2 (isocitrate dehydrogenase (NADP(+)) 2).