gene: wnk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables molecular condensate scaffold activity. Involved in several processes, including cell volume homeostasis; cellular hyperosmotic response; and multicellular organismal-level water homeostasis. Predicted to be located in cytoplasm. Expressed in body wall musculature; excretory cell; and spermatheca. Used to study pseudohypoaldosteronism. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 2A; hypertension; and pseudohypoaldosteronism. Is an ortholog of several human genes including WNK1 (WNK lysine deficient protein kinase 1); WNK3 (WNK lysine deficient protein kinase 3); and WNK4 (WNK lysine deficient protein kinase 4).