gene: paf-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables 1-alkyl-2-acetylglycerophosphocholine esterase activity. Involved in lipid catabolic process and morphogenesis of embryonic epithelium. Predicted to be located in cytosol and endoplasmic reticulum membrane. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and glomerulonephritis (multiple). Is an ortholog of human PAFAH2 (platelet activating factor acetylhydrolase 2) and PLA2G7 (phospholipase A2 group VII).