gene: pde-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity. Involved in several processes, including determination of adult lifespan; negative regulation of cGMP-mediated signaling; and response to alkaline pH. Human ortholog(s) of this gene implicated in hypertension and brachydactyly syndrome. Is an ortholog of human PDE3A (phosphodiesterase 3A) and PDE3B (phosphodiesterase 3B).