gene: slo-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables calcium-activated potassium channel activity and outward rectifier potassium channel activity. Involved in positive regulation of neurotransmitter secretion and potassium ion transport. Located in axon. Expressed in amphid neurons; body wall musculature; motor neurons; nerve ring; and vulval muscle. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 5; developmental and epileptic encephalopathy 14; and developmental and epileptic encephalopathy 57. Is an ortholog of human KCNT1 (potassium sodium-activated channel subfamily T member 1) and KCNT2 (potassium sodium-activated channel subfamily T member 2).