Enriched in several structures, including NSM; intestine; sensory neurons; tail hypodermis; and ventral cord blast cell based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including
daf-16;
daf-2; and
skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PH-like domain superfamily; Pleckstrin homology domain; and PH domain. Is an ortholog of human PLEKHD1 (pleckstrin homology and coiled-coil domain containing D1).