gene: twnk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 5'-3' DNA helicase activity and single-stranded DNA binding activity. Predicted to be involved in mitochondrial DNA replication. Predicted to be located in mitochondrial nucleoid. Human ortholog(s) of this gene implicated in Perrault syndrome; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 3; and mitochondrial DNA depletion syndrome 7. Is an ortholog of human TWNK (twinkle mtDNA helicase).