gene: mrp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in dauer larval development; regulatory ncRNA-mediated post-transcriptional gene silencing; and stress response to metal ion. Located in plasma membrane. Expressed in several structures, including intestine; pharyngeal-intestinal valve; pharynx; rectal valve cell; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including bile duct disease (multiple); leukemia (multiple); and lung disease (multiple). Is an ortholog of human ABCC3 (ATP binding cassette subfamily C member 3).
sequence feature: WBsf717301
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=F57C12.5. Surounding gene organisation=divergent