gene: par-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables myosin II tail binding activity; protein serine/threonine kinase activity; and ubiquitin protein ligase binding activity. Involved in several processes, including cell fate commitment; embryonic pattern specification; and vulval development. Located in P granule and cell cortex. Expressed in germ line and vulva. Human ortholog(s) of this gene implicated in visual impairment and progressive phthisis bulbi. Is an ortholog of human MARK1 (microtubule affinity regulating kinase 1).