gene: mls-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including establishment of mitotic spindle orientation; neuron differentiation involved in amphid sensory organ development; and regulation of cell differentiation. Located in nucleus. Expressed in several structures, including AB lineage cell; AWC-ON; M.dla; head; and somatic nervous system. Human ortholog(s) of this gene implicated in oculoauricular syndrome. Is an ortholog of human HMX1 (H6 family homeobox 1).