gene: adsl-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity and N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity. Predicted to be involved in 'de novo' AMP biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in adenylosuccinase lyase deficiency; breast cancer; and prostate cancer. Is an ortholog of human ADSL (adenylosuccinate lyase).