gene: rde-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables double-stranded RNA binding activity; protein homodimerization activity; and single-stranded RNA binding activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing and siRNA processing. Part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in dystonia 16. Is an ortholog of human PRKRA (protein activator of interferon induced protein kinase EIF2AK2) and TARBP2 (TARBP2 subunit of RISC loading complex).