gene: pgrn-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be located in extracellular region. Expressed in coelomocyte; neurons; and pseudocoelom. Used to study frontotemporal dementia. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Grn-related frontotemporal lobar degeneration with Tdp43 inclusions; and multiple sclerosis (multiple). Is an ortholog of human GRN (granulin precursor).