gene: unc-42 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including larval locomotory behavior; neuron differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in hypodermis; nerve ring; and neurons. Human ortholog(s) of this gene implicated in hypogonadism and panhypopituitarism. Is an ortholog of several human genes including ESX1 (ESX homeobox 1); PROP1 (PROP paired-like homeobox 1); and RHOXF2 (Rhox homeobox family member 2).