- strain: NJ261
Caenorhabditis elegans - strain: NM467
Caenorhabditis elegans - gene: K02F3.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 3'-5' DNA helicase activity and four-way junction helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication and double-strand break repair via homologous recombination. Predicted to be located in chromosome and cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and pancreatic cancer. Is an ortholog of human RECQL (RecQ like helicase).
- strain: WM107
Caenorhabditis elegans - gene: aly-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human ALYREF (Aly/REF export factor).
- gene: atf-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in hydrogen sulfide biosynthetic process and positive regulation of gene expression. Located in nucleus. Human ortholog(s) of this gene implicated in prostate carcinoma. Is an ortholog of human ATF4 (activating transcription factor 4) and ATF5 (activating transcription factor 5).
- gene: msh-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable four-way junction DNA binding activity and mismatched DNA binding activity. Involved in maintenance of DNA repeat elements and mismatch repair. Predicted to be located in nucleus. Predicted to be part of MutSalpha complex. Used to study Lynch syndrome. Human ortholog(s) of this gene implicated in several diseases, including colorectal carcinoma; hereditary nonpolyposis colorectal cancer type 5; and mismatch repair cancer syndrome. Is an ortholog of human MSH6 (mutS homolog 6).
- gene: cogc-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be part of Golgi transport complex. Expressed in gonad. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIi. Is an ortholog of human COG5 (component of oligomeric golgi complex 5).
- gene: aly-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human ALYREF (Aly/REF export factor).