gene: plk-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mitotic spindle organization. Predicted to be located in several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Human ortholog(s) of this gene implicated in several diseases, including breast carcinoma; reproductive organ cancer (multiple); and urinary bladder cancer. Is an ortholog of human PLK1 (polo like kinase 1).
expression cluster: WBPaper00031477:Up_deps-1_vs_WT Confidence levels were determined using a z test performed in Excel followed by a correction for multiple testing in which the P-value was multiplied by 17,539 (the number of genes on the microarrays). After this correction, all genes with a fold change of >1.8-fold, P < 0.05 were selected for analysis.
Genes upregulated in deps-1(bn124) relative to wild type.