Enables uracil DNA N-glycosylase activity. Involved in base-excision repair. Located in nucleus. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Is an ortholog of human UNG (uracil DNA glycosylase).
hierachical clustering
Genes involved in oxidative stress responses and lifespan regulation that were differentially regulated in ung-1(7600). These are only part of the 1680 genes differentially regulated by ung-1(7600).
Peptide identifications were imported into Progenesis QI and associated with aligned peptide precursor intensities. Protein quantifications were filtered to require a minimum of two unique quantifiable peptides. Comparison of differences between sample groups was also performed in QI by ANOVA testing with multiple-test-correction to q-values.
Proteins interacting with GST-UNG-1 comparing to the control GST-OCT1-17aa.