Predicted to enable protein serine/threonine kinase activity. Involved in embryo development and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CHEK1 (checkpoint kinase 1).
This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=Y39H10A.5. Surounding gene organisation=divergent
This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=Y39H10A.3. Surounding gene organisation=divergent