Predicted to enable protein transmembrane transporter activity; ribosome binding activity; and signal sequence binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation and post-translational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be part of Sec61 translocon complex. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Is an ortholog of human SEC61A1 (SEC61 translocon subunit alpha 1) and SEC61A2 (SEC61 translocon subunit alpha 2).