Enables damaged DNA binding activity and transferase activity, transferring alkyl or aryl (other than methyl) groups. Involved in DNA dealkylation involved in DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endocrine gland cancer (multiple); and high grade glioma (multiple). Is an ortholog of human MGMT (O-6-methylguanine-DNA methyltransferase).
Predicted to be involved in intracellular transport and protein secretion. Predicted to be located in Golgi membrane. Is an ortholog of human TMEM167A (transmembrane protein 167A).