Predicted to enable leucine binding activity and oxidoreductase activity, acting on peroxide as acceptor. Predicted to be involved in several processes, including cellular response to leucine; cellular response to leucine starvation; and negative regulation of TORC1 signaling. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SESN1 (sestrin 1).
This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=Y74C9A.5. Surounding gene organisation=divergent