gene: nhr-253 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in ASEL; ASER; and neurons. Human ortholog(s) of this gene implicated in cholestasis (multiple); liver disease (multiple); and non-alcoholic steatohepatitis. Is an ortholog of human NR1H4 (nuclear receptor subfamily 1 group H member 4) and NR1I3 (nuclear receptor subfamily 1 group I member 3).