gene: unc-16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables kinase binding activity; kinesin binding activity; and signaling adaptor activity. Involved in several processes, including defecation; egg-laying behavior; and regulation of JNK cascade. Located in axon; cell body; and cytoplasm. Expressed in body wall musculature; hypodermis; intestine; and nervous system. Human ortholog(s) of this gene implicated in endometrial cancer; hepatocellular carcinoma; and liver cirrhosis. Is an ortholog of human MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3).