- gene: sphk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable D-erythro-sphingosine kinase activity and acetyltransferase activity. Involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion. Located in several cellular components, including mitochondrion; neuronal cell body; and presynaptic periactive zone. Expressed in several structures, including body wall musculature; excretory canal; intestine; linker cell; and neurons. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human SPHK1 (sphingosine kinase 1) and SPHK2 (sphingosine kinase 2).
- sequence feature: WBsf650944
Caenorhabditis elegans Clustered region of TSS sites. Number of tags=274. Shape score=0.30292. Assignement type=wormbase_tss. Mode position in cluster=58.
- sequence feature: WBsf646291
Caenorhabditis elegans Clustered region of TSS sites. Number of tags=274. Shape score=0.215328. Assignement type=wormbase_tss. Mode position in cluster=73.
- sequence feature: WBsf643276
Caenorhabditis elegans Clustered region of TSS sites. Number of tags=274. Shape score=0.240876. Assignement type=wormbase_tss. Mode position in cluster=29.
- sequence feature: WBsf695358
Caenorhabditis elegans Clustered region of TSS sites. Number of tags=274. Shape score=0.116788. Assignement type=unassigned. Mode position in cluster=228.
- sequence feature: WBsf713008
Caenorhabditis elegans Clustered region of TSS sites. Number of tags=274. Shape score=0.142336. Assignement type=unassigned. Mode position in cluster=36.
- sequence feature: WBsf644179
Caenorhabditis elegans Clustered region of TSS sites. Number of tags=274. Shape score=0.29562. Assignement type=wormbase_tss. Mode position in cluster=45.
- sequence feature: WBsf655378
Caenorhabditis elegans Clustered region of TSS sites. Number of tags=274. Shape score=0.29927. Assignement type=raft_to_wormbase_tss. Mode position in cluster=48.
- sequence feature: WBsf708490
Caenorhabditis elegans Clustered region of TSS sites. Number of tags=274. Shape score=0.364964. Assignement type=unassigned. Mode position in cluster=84.