C. elegans exhibit an age-dependent mechanical stress response to blunt force injury. Stress responses are often defined in part by an elicited cellular transcriptional response. We find in C. elegans that mechanical stress by blunt trauma induces a distinct and age-dependent transcriptional program.
Illumina HiSeq 2000 paired end sequencing; Illumina sequencing of C. elegans dauer entry daf-2(el370) sample 1-1 DauerEntryDAF2-1-1 polyA+ 101bp PE RNAseq random fragment library RW0001
Illumina HiSeq 2000 paired end sequencing; Illumina sequencing of C. elegans dauer entry daf-2(el370) sample 1-1 DauerEntryDAF2-1-1 polyA+ 100bp SE RNAseq random fragment library RW0001
Illumina HiSeq 2000 paired end sequencing; Illumina sequencing of C. elegans dauer entry daf-2(el370) sample 1-1 DauerEntryDAF2-1-1 polyA+ 100bp PE RNAseq random fragment library RW0001
Illumina HiSeq 2000 paired end sequencing; Illumina sequencing of C. elegans dauer entry daf-2(el370) sample 1-1 DauerEntryDAF2-1-1 polyA+ 101bp SE RNAseq random fragment library RW0001
We showed that KLF-1 is needed for longevity of isp-1(qm150);ctb-1(qm189) mutant specifically in adulthood. We aimed to determine the expression changes that occur specifically upon adulthood klf-1 RNAi compared to developmental RNAi that did not affect the lifespan of isp-1(qm150);ctb-1(qm189) mutant.