The hlh-30 gene encodes a C. elegans basic-helix-loop-helix (bHLH) transcription factor; We compared RNA from wild type worms and worms mutant for the hlh-30 gene to identify putative target genes of the HLH-30 transcription factor.
In Caenorhabditis elegans, the six proteins that make up the REF-1 family are HES homologs that act in both Notch dependent and Notch-independent pathways to regulate embryonic events. To further our understanding of how the REF-1 family works to coordinate post-embryonic cellular events, we performed transcriptome analysis of HLH-25 and HLH-29 mutant strains.
A quantitative shotgun proteomics approach using 15N-based metabolic labeling was conducted at 20, 40, and 60 h during development starting with L1-larvae of N2 animals.
A quantitative shotgun proteomics approach using 15N-based metabolic labeling was conducted at 20, 40, and 60 h during development starting with L1-larvae of N2 animals.
A quantitative shotgun proteomics approach using 15N-based metabolic labeling was conducted at 20, 40, and 60 h during development starting with L1-larvae of N2 animals.
A quantitative shotgun proteomics approach using 15N-based metabolic labeling was conducted at 20, 40, and 60 h during development starting with L1-larvae of N2 animals.
A quantitative shotgun proteomics approach using 15N-based metabolic labeling was conducted at 20, 40, and 60 h during development starting with L1-larvae of N2 animals.
A quantitative shotgun proteomics approach using 15N-based metabolic labeling was conducted at 20, 40, and 60 h during development starting with L1-larvae of N2 animals.
A quantitative shotgun proteomics approach using 15N-based metabolic labeling was conducted at 20, 40, and 60 h during development starting with L1-larvae of pept-1(lg601) animals.
A quantitative shotgun proteomics approach using 15N-based metabolic labeling was conducted at 20, 40, and 60 h during development starting with L1-larvae of pept-1(lg601) animals.