- WBPaper00064939:vit-5(RNAi)_upregulated
DESeq R package (1.18.0), P < 0.05 and fold change > 2
Transcripts that showed significantly increased expression in vit-5(RNAi) comparing to in N2 animals injected with empty vector.
- WBPaper00064939:vit-5(RNAi)_downregulated
DESeq R package (1.18.0), P < 0.05 and fold change > 2
Transcripts that showed significantly decreased expression in vit-5(RNAi) comparing to in N2 animals injected with empty vector.
- WBPaper00051305:vit-2(ac3)_upregulated
Differential gene expression analysis was then performed on normalized samples. Genes exhibiting at least twofold change and a false-discovery rate (FDR) of 1% or less were considered differentially expressed.
Transcripts that showed significantly increased expression in vit-2(ac3); zcIs4, comparing to parenting strain SJ4005 [zcIs4].
- WBPaper00061527:vit-2-vit-4_22519
All available microarray datasets for the GPL200 platform (Affymetrix C. elegans Genome Array) were obtained from the GEO repository. This included 2243 individual microarray experiments. These were normalized against each other with the software RMAexpress (Bolstad, 2014). Based on these normalized values, Pearsons correlation coefficients were obtained for each probe-probe pair of the 22,620 probes represented on this array type. The resulting list of correlation coefficients was then ranked to generate the ranked coexpression database with information on each probe represented on the GPL200 platform.
Coexpression clique No. 280, vit-2-vit-4_22519, on the genome-wide coexpression clique map for the nematode GPL200 platform.
- WBPaper00051305:vit-2(ac3)_downregulated
Differential gene expression analysis was then performed on normalized samples. Genes exhibiting at least twofold change and a false-discovery rate (FDR) of 1% or less were considered differentially expressed.
Transcripts that showed significantly decreased expression in vit-2(ac3); zcIs4, comparing to parenting strain SJ4005 [zcIs4].
- WBPaper00055013:HMG-3_interacting_protein
N.A.
Proteins that interact with HMG-3-HA in BAT1753 [hmg-3(bar24[hmg-3-3xHA]) I] at L4 larva stage according to Co-Immunoprecipitation with subsequent Mass Spectrometry analysis.