- WBPaper00049006:nicotine_upregulated_F2
Statistical analysis was based on t-test for independent samples via SPSS to compare each of the nicotine treatments with control (i.e. low vs. control and high vs. control). Welch test correction was performed to account for unequal variance in each of the compared groups (control and treatment). In addition, to increase the statistical stringency, miRNAs differential expression was deemed significant only if it fulfilled two criteria: p value , 0.05 and expression changed by at least 50% relative to control.
miRNAs in F2 generation up regulated by exposure to 20uM and 20mM nicotine during F0 generation.
- WBPaper00049006:nicotine_upregulated_F1
Statistical analysis was based on t-test for independent samples via SPSS to compare each of the nicotine treatments with control (i.e. low vs. control and high vs. control). Welch test correction was performed to account for unequal variance in each of the compared groups (control and treatment). In addition, to increase the statistical stringency, miRNAs differential expression was deemed significant only if it fulfilled two criteria: p value , 0.05 and expression changed by at least 50% relative to control.
miRNAs in F1 generation up regulated by exposure to 20uM and 20mM nicotine during F0 generation.
- WBPaper00049006:nicotine_downregulated_F2
Statistical analysis was based on t-test for independent samples via SPSS to compare each of the nicotine treatments with control (i.e. low vs. control and high vs. control). Welch test correction was performed to account for unequal variance in each of the compared groups (control and treatment). In addition, to increase the statistical stringency, miRNAs differential expression was deemed significant only if it fulfilled two criteria: p value , 0.05 and expression changed by at least 50% relative to control.
miRNAs in F2 generation down regulated by exposure to 20uM and 20mM nicotine during F0 generation.
- WBPaper00049006:nicotine_downregulated_F1
Statistical analysis was based on t-test for independent samples via SPSS to compare each of the nicotine treatments with control (i.e. low vs. control and high vs. control). Welch test correction was performed to account for unequal variance in each of the compared groups (control and treatment). In addition, to increase the statistical stringency, miRNAs differential expression was deemed significant only if it fulfilled two criteria: p value , 0.05 and expression changed by at least 50% relative to control.
miRNAs in F1 generation down regulated by exposure to 20uM and 20mM nicotine during F0 generation.
- WBPaper00041267:SpaceFlight_Downregulated
Genes increased by more than 2 fold expression in the spaceflight relative to the ground control are regarded as differentially expressed.
Genes decreased to less than half expressionin the spaceflight relative to the ground control.
- WBPaper00045774:clk-1_upregulated_CoQ10_independent
Fold-changes of intensities were calculated from the arithmetic mean of gene expression values between experimental and corresponding control group. Fold change >= 1.5 was used as cut-off.
Up-regulated genes (fold change > 1.5), non-rescued by CoQ10 supplementation (-10 +10 %) in two CoQ-deficient clk-1 mutant strains (e2519, qm30) compared to wild types N2.
- WBPaper00045774:clk-1_downregulated_CoQ10_independent
Fold-changes of intensities were calculated from the arithmetic mean of gene expression values between experimental and corresponding control group. Fold change >= 1.5 was used as cut-off.
Down-regulated genes (fold change > 1.5), non-rescued by CoQ10 supplementation (-10 +10 %) in two CoQ-deficient clk-1 mutant strains (e2519, qm30) compared to wild types N2.
- WBPaper00041267:SpaceFlight_Upregulated
Genes increased by more than 2 fold expression in the spaceflight relative to the ground control are regarded as differentially expressed.
Genes increased by more than 2 fold expression in the spaceflight relative to the ground control.