Predicted to enable transcription cis-regulatory region binding activity. Involved in determination of adult lifespan; programmed cell death; and transdifferentiation. Located in nucleus. Part of MLL3/4 complex. Expressed in germ line. Is an ortholog of human ASH2L (ASH2 like, histone lysine methyltransferase complex subunit).
Is affected by several genes including pqm-1; ash-2; and adr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fluoranthene and Sirolimus based on microarray studies.
Enriched in ADL; ASH; and PHA based on single-cell RNA-seq studies. Is affected by several genes including daf-12; hpl-2; and dpy-21 based on RNA-seq and microarray studies.
Enriched in ASH based on single-cell RNA-seq studies. Is affected by eat-2; etr-1; and mrps-5 based on microarray and RNA-seq studies. Is affected by nitroguanidine based on microarray studies.
Enriched in neurons based on microarray studies. Is affected by fbf-1; ash-2; and tdp-1 based on microarray studies. Is affected by four chemicals including Humic Substances; Sirolimus; and allantoin based on microarray and RNA-seq studies.
Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Located in cilium. Expressed in head and tail.