Involved in positive regulation of gene expression. Located in apical plasma membrane; apicolateral plasma membrane; and nucleus. Expressed in intestine and pharynx. Used to study cerebral cavernous malformation. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 1. Is an ortholog of human KRIT1 (KRIT1 ankyrin repeat containing).
Enriched in neurons based on RNA-seq studies. Is affected by kri-1 and lbp-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies.
Enriched in neurons based on RNA-seq studies. Is affected by kri-1 and mpk-2 based on RNA-seq studies. Is affected by Tunicamycin and Cadmium Chloride based on RNA-seq studies.