Involved in negative regulation of gene expression; nervous system development; and regulation of protein localization to synapse. Located in nucleus. Expressed in ganglia; touch receptor neurons; and vulva. Is an ortholog of human SSBP3 (single stranded DNA binding protein 3).
Enables DNA-binding transcription factor activity; DNA-binding transcription factor binding activity; and LIM domain binding activity. Involved in several processes, including mechanosensory behavior; positive regulation of vulval development; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in several structures, including AIY; body wall musculature; gonad; neurons; and vulval muscle.
Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endometrial cancer; and primary autosomal recessive microcephaly 1. Is an ortholog of human MCPH1 (microcephalin 1).