Enables dynein complex binding activity. Involved in several processes, including gonad development; microtubule cytoskeleton organization; and regulation of protein localization. Located in cell cortex; condensed chromosome; and spindle.
Is affected by several genes including met-2; spr-5; and lin-52 based on RNA-seq studies. Is affected by bortezomib and Tamoxifen based on RNA-seq studies.
Enables protein kinase activity. Involved in several processes, including GABAergic synaptic transmission; regulation of cellular localization; and regulation of synapse organization. Located in axon and synapse. Used to study epilepsy and lissencephaly. Human ortholog(s) of this gene implicated in Alzheimer's disease and lissencephaly 7 with cerebellar hypoplasia. Is an ortholog of human CDK5 (cyclin dependent kinase 5).