Enables armadillo repeat domain binding activity. Involved in molting cycle and positive regulation of nematode male tail tip morphogenesis. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including excretory system; gonad; hypodermal cell; tail; and vulval precursor cell. Human ortholog(s) of this gene implicated in several diseases, including Zellweger syndrome; gonadal dysgenesis (multiple); and primary ovarian insufficiency 7. Is an ortholog of human NR5A2 (nuclear receptor subfamily 5 group A member 2).
Is affected by tdp-1; nhr-25; and nuo-6 based on microarray studies. Is affected by Atrazine; fluoranthene; and Microcystin-LR based on microarray studies.
Is affected by several genes including pmk-1; aak-2; and nhr-25 based on microarray studies. Is affected by four chemicals including Selenium; Colistin; and Sirolimus based on microarray studies.
Is affected by several genes including eat-2; nhr-25; and dpy-21 based on microarray and RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies.
Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including rrf-3; nhr-25; and his-72 based on RNA-seq and microarray studies.
Is affected by several genes including clk-1; mex-3; and nhr-25 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies.
Is affected by several genes including daf-16; clk-1; and nhr-25 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.