Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in peroxisomal membrane. Is an ortholog of human PEX11G (peroxisomal biogenesis factor 11 gamma).
Predicted to enable tryptophan-tRNA ligase activity. Predicted to be involved in mitochondrial tryptophanyl-tRNA aminoacylation. Predicted to be located in mitochondrial matrix. Used to study obesity. Is an ortholog of human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 3 and Charcot-Marie-Tooth disease type 4F. Is an ortholog of human AHNAK2 (AHNAK nucleoprotein 2) and PRX (periaxin).
Enables peroxisome targeting sequence binding activity. Involved in nematode larval development and protein import into peroxisome matrix. Predicted to be located in cytosol and peroxisomal membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Is an ortholog of human PEX5 (peroxisomal biogenesis factor 5).
Involved in nematode larval development. Predicted to be located in peroxisomal membrane. Predicted to be part of peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 11A. Is an ortholog of human PEX13 (peroxisomal biogenesis factor 13).