Contributes to microtubule severing ATPase activity. Involved in embryo development; meiotic spindle organization; and microtubule depolymerization. Located in cytoplasm; nucleus; and spindle pole. Part of katanin complex.
Is affected by Cbr-htz-1 and Cbr-spr-4 based on RNA-seq studies. Is an ortholog of C. elegans mei-2. In C. elegans, mei-2 is involved in embryo development; meiotic spindle organization; and microtubule depolymerization.
Contributes to microtubule severing ATPase activity. Involved in microtubule depolymerization. Part of katanin complex. Expressed in amphid neurons; inner labial neurons; outer labial neurons; and phasmid neurons.
Contributes to microtubule severing ATPase activity. Involved in microtubule depolymerization. Part of katanin complex. Human ortholog(s) of this gene implicated in lissencephaly 6. Is an ortholog of human KATNB1 (katanin regulatory subunit B1).
Predicted to enable microtubule binding activity. Is an ortholog of C. elegans mei-2. In C. elegans, mei-2 is involved in embryo development; meiotic spindle organization; and microtubule depolymerization.