asm-1

Caenorhabditis elegans

Enables sphingomyelin phosphodiesterase activity. Involved in ceramide biosynthetic process and sphingomyelin catabolic process. Located in extracellular region and lysosome. Human ortholog(s) of this gene implicated in Niemann-Pick disease type A and Niemann-Pick disease type B. Is an ortholog of human SMPD1 (sphingomyelin phosphodiesterase 1).