trim-21 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm. Expressed in several structures, including pharyngeal muscle cell and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; and hematologic cancer (multiple). Is an ortholog of several human genes including MEFV (MEFV innate immunity regulator, pyrin); TRIM21 (tripartite motif containing 21); and TRIM27 (tripartite motif containing 27).