Enriched in several structures, including ABalppappa; ABarappppa; ABplpppaapa; germ line; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including
daf-2;
sir-2.1; and
pmk-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; Rifampin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Human PYGO1 enables methylated histone binding activity. Is an ortholog of human PYGO1 (pygopus family PHD finger 1) and PYGO2 (pygopus family PHD finger 2).