mak-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables mitogen-activated protein kinase binding activity. Involved in several processes, including behavioral response to nicotine; positive regulation of 3'-UTR-mediated mRNA stabilization; and regulation of axon extension. Located in cytoplasm; nucleus; and synapse. Expressed in body wall musculature; intestine; and pharynx. Human ortholog(s) of this gene implicated in patterned macular dystrophy 3. Is an ortholog of human MAPKAPK2 (MAPK activated protein kinase 2) and MAPKAPK3 (MAPK activated protein kinase 3).