gpb-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable signaling receptor complex adaptor activity. Involved in several processes, including establishment of mitotic spindle orientation; negative regulation of locomotion; and regulation of egg-laying behavior. Predicted to be located in cytoplasm. Predicted to be part of heterotrimeric G-protein complex. Expressed in several structures, including body wall musculature; germ line; intestine; pharynx; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease dominant intermediate F; artery disease (multiple); and hematologic cancer (multiple). Is an ortholog of human GNB1 (G protein subunit beta 1) and GNB4 (G protein subunit beta 4).