unc-26 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in several processes, including cellular component organization; nitrogen compound transport; and regulation of locomotion. Located in synapse. Expressed in tail and ventral cord neurons. Used to study Down syndrome and early-onset Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease 20 and developmental and epileptic encephalopathy 53. Is an ortholog of human SYNJ1 (synaptojanin 1).