Enables protein serine/threonine kinase activity. Involved in several processes, including engulfment of apoptotic cell; left/right axis specification; and regulation of cellular component organization. Predicted to be located in cytosol and nucleus. Expressed in distal tip cell; seam cell; and sperm. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; bipolar disorder; carcinoma (multiple); and degenerative disc disease. Is an ortholog of human GSK3A (glycogen synthase kinase 3 alpha) and GSK3B (glycogen synthase kinase 3 beta).
Predicted to enable inositol-polyphosphate 5-phosphatase activity. Expressed in pharyngeal muscle cell and rectal epithelium. Is an ortholog of human INPP5A (inositol polyphosphate-5-phosphatase A).
Enables GTPase activating protein binding activity. Involved in molting cycle. Is an ortholog of human RABEP1 (rabaptin, RAB GTPase binding effector protein 1).
Predicted to enable inositol-polyphosphate 5-phosphatase activity. Involved in negative regulation of epidermal growth factor receptor signaling pathway and ovulation. Expressed in spermatheca. Is an ortholog of human INPP5A (inositol polyphosphate-5-phosphatase A).
Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to be located in dendrite. Expressed in neurons.
Enables identical protein binding activity. Involved in centrosome cycle; positive regulation of mitotic cell cycle, embryonic; and protein localization to organelle. Located in centrosome and cytoplasm.