tra-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables transmembrane signaling receptor activity. Involved in developmental process involved in reproduction and oocyte fate determination. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. Expressed in germ line.
F47B7.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
pmk-1;
clk-1; and
mdt-15 based on tiling array; microarray; and RNA-seq studies. Is affected by resveratrol; Atrazine; and nitroguanidine based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
T10D4.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
eat-2;
alg-1; and
csr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
T14G12.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
rrf-3;
sir-2.1; and
pmk-1 based on RNA-seq and microarray studies. Is affected by glycine and multi-walled carbon nanotube based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
Y73F8A.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in male based on RNA-seq studies. Is affected by several genes including
csr-1;
hpl-2; and
cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F59A6.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
eat-2;
sir-2.1; and
sek-1 based on RNA-seq; tiling array; and microarray studies. Is affected by six chemicals including Ethanol; tryptophan; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F16G10.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in male based on RNA-seq studies. Is affected by several genes including
elt-2;
csr-1; and
hpl-2 based on tiling array and RNA-seq studies. Is affected by Chlorpyrifos and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
R03H10.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in coelomocyte and in male based on tiling array and RNA-seq studies. Is affected by several genes including
eat-2;
pgl-1; and
alg-1 based on RNA-seq and microarray studies. Is affected by resveratrol; cadmium; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F47B7.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
daf-16;
daf-12; and
eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by glycine and nitroguanidine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F16G10.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in AFD and NSM based on tiling array and RNA-seq studies. Is affected by several genes including
elt-2;
clk-1; and
lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
C52E2.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
sir-2.1;
osm-3; and
mut-2 based on microarray and RNA-seq studies. Is affected by four chemicals including aldicarb; Rifampin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
T14G12.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in AVE based on tiling array studies. Is affected by several genes including
daf-12;
sir-2.1; and
aak-2 based on microarray; tiling array; and RNA-seq studies. Is affected by Ag nanoparticles based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
R52.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in germ line based on RNA-seq studies. Is affected by several genes including
csr-1;
mex-3; and
hda-1 based on tiling array and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F16G10.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in pharynx and in male based on RNA-seq studies. Is affected by several genes including
rrf-3;
sir-2.1; and
tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F16G10.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in NSM and hypodermis based on tiling array studies. Is affected by
drh-3;
eat-2; and
spn-4 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
ZC204.17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in male based on RNA-seq studies. Is affected by several genes including
daf-2;
rrf-3; and
eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
tra-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cysteine-type endopeptidase activity. Involved in proteolysis and sex determination. Predicted to be located in cytoplasm. Expressed in several structures, including excretory cell; hypodermis; intestine; ventral nerve cord; and vulva. Human ortholog(s) of this gene implicated in neovascular inflammatory vitreoretinopathy. Is an ortholog of human CAPN5 (calpain 5).
F43C11.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in ALM; BDU; and rectal epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including
eat-2;
pgl-1; and
alg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
R52.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in ABplppppaa and ABprppppaa based on single-cell RNA-seq studies. Is affected by several genes including
clk-1;
csr-1; and
mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including Ag nanoparticles; cadmium; and tetrabromobisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F16G10.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in RICL and RICR based on single-cell RNA-seq studies. Is affected by several genes including
eat-2;
sir-2.1; and
mex-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
tra-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process. Located in cytoplasm and nucleus. Expressed in several structures, including AWA; germ line; gonad; intestine; and somatic cell. Human ortholog(s) of this gene implicated in several diseases, including Culler-Jones syndrome; gastrointestinal system cancer (multiple); and synostosis (multiple). Is an ortholog of human GLI1 (GLI family zinc finger 1); GLI2 (GLI family zinc finger 2); and GLI3 (GLI family zinc finger 3).
F47B7.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in DA neuron and VA neuron based on tiling array studies. Is affected by several genes including
age-1;
eat-2; and
sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
T10D4.15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in ASH; neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including
hsf-1;
rrf-3; and
eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F16G10.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including
daf-16;
let-60; and
daf-12 based on microarray and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; Alovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
sup-26 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables mRNA 3'-UTR binding activity. Involved in negative regulation of translation. Located in cytoplasm. Expressed in several structures, including gonad. Is an ortholog of human RBMS1 (RNA binding motif single stranded interacting protein 1); RBMS2 (RNA binding motif single stranded interacting protein 2); and RBMS3 (RNA binding motif single stranded interacting protein 3).
F16G10.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in AVE based on tiling array studies. Is affected by several genes including
daf-2;
eat-2; and
sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F16G10.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including
daf-16;
daf-12; and
rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
T10D4.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including
eat-2;
sir-2.1; and
clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including D-glucose; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F43C11.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in AVE; NSM; and in male based on tiling array and RNA-seq studies. Is affected by several genes including
rrf-3;
eat-2; and
tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F07E5.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in PLM and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including
daf-16;
daf-2; and
daf-12 based on microarray and RNA-seq studies. Is affected by four chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and glycine based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
ZK250.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in AFD; AIM; Z1.p; Z4.a; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including
daf-2;
lin-35; and
csr-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; dafa#1; and adsorbable organic bromine compound based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F43C11.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in NSM; germ line; male-specific anatomical entity; and in male based on proteomic; tiling array; RNA-seq; and microarray studies. Is affected by several genes including
rrf-3;
eat-2; and
tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
ehn-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metal ion binding activity. Involved in gonad development and positive regulation of gene expression. Located in nucleus. Expressed in Z1; Z4; and somatic gonad precursor.
F16G10.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in NSM; intestine; and in male based on tiling array and RNA-seq studies. Is affected by several genes including
daf-2;
eat-2; and
elt-2 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
F43C11.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in PVD; germ line; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including
rrf-3;
eat-2; and
sir-2.1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
T14G12.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in ABplpaapap; ABprpaapap; head mesodermal cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including
rrf-3;
eat-2; and
lin-35 based on RNA-seq studies. Is affected by four chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
R05D8.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in germline precursor cell; hypodermis; intestine; and ventral nerve cord based on tiling array and single-cell RNA-seq studies. Is affected by several genes including
clk-1;
dpy-7; and
aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
Y25C1A.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in AUA; cholinergic neurons; excretory cell; pharyngeal cell; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including
daf-16;
daf-12; and
rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
fem-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein phosphatase binding activity. Involved in several processes, including proteasome-mediated ubiquitin-dependent protein catabolic process; regulation of germ cell proliferation; and sex determination. Located in protein-containing complex. Part of Cul2-RING ubiquitin ligase complex. Expressed in several structures, including germ line. Is an ortholog of human FEM1A (
fem-1 homolog A) and FEM1C (
fem-1 homolog C).
Ppa-tra-1.1 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
CRE14683 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: TRA-1 regulated; Domain of unknown function (DUF281); TRA-1 regulated protein R03H10.4; and Domain of unknown function DUF281. Is an ortholog of C. elegans T10D4.11.
CRE14642 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: TRA-1 regulated; Domain of unknown function (DUF281); TRA-1 regulated protein R03H10.4; and Domain of unknown function DUF281. Is an ortholog of C. elegans T10D4.11.
asp-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable aspartic-type endopeptidase activity. Involved in programmed necrotic cell death. Located in lysosome. Expressed in intestine and uterus. Is an ortholog of human NAPSA (napsin A aspartic peptidase).
Cbr-tra-1 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
asp-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable aspartic-type endopeptidase activity. Involved in programmed necrotic cell death. Located in lysosome. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; and neuronal ceroid lipofuscinosis 10. Is an ortholog of human CTSD (cathepsin D).
fog-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transcription corepressor activity. Involved in cell fate specification; developmental process involved in reproduction; and positive regulation of oocyte development. Located in cytoplasm and nuclear periphery. Expressed in germ line. Is an ortholog of human TOB1 (transducer of ERBB2, 1).
WDR79 [Search on AGR]
Drosophila melanogaster WD repeat domain 79 (WDR79) encodes a protein that binds to the CAB box of the Small Cajal body-specific RNAs (scaRNAs). It is a component of the nuclear Cajal body (CB) and is required for CB formation.
fog-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in several processes, including cytoplasmic streaming; developmental process involved in reproduction; and positive regulation of cell differentiation. Located in cytoplasm. Expressed in germ line.
Cre-tra-1.1 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
Ovo-tra-1 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
Cbn-tra-1 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
SRAE_2000328900 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
TMUE_2000009504 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
CBN09408 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
Cjp-tra-1 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
Cre-tra-1.2 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
egl-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in several processes, including actin filament depolymerization; apoptotic process; and positive regulation of cellular component organization. Located in cytosol; mitochondrion; and presynapse. Expressed in several structures, including ABalappaapp; ABaraapapaad; HSN; URX; and proctodeal cell.
Cbr-tra-2 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in hermaphrodite germ-line sex determination and hermaphrodite somatic sex determination. Is an ortholog of C. elegans
tra-2. In C. elegans,
tra-2 is involved in developmental process involved in reproduction and oocyte fate determination.
Bma-tra-1 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
Cre-tra-2 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in hermaphrodite germ-line sex determination and hermaphrodite somatic sex determination. Is an ortholog of C. elegans
tra-2. In C. elegans,
tra-2 is involved in developmental process involved in reproduction and oocyte fate determination.
Ppa-tra-1.2 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Ribosomal protein S7p/S5e; Zinc finger, C2H2 type; Ribosomal protein S7 domain superfamily; Zinc finger C2H2 superfamily; Ribosomal protein S7 domain; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-1. In C. elegans,
tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.
Cbn-tra-2 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in hermaphrodite germ-line sex determination and hermaphrodite somatic sex determination. Is an ortholog of C. elegans
tra-2. In C. elegans,
tra-2 is involved in developmental process involved in reproduction and oocyte fate determination.
Cjp-tra-2 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in hermaphrodite germ-line sex determination and hermaphrodite somatic sex determination. Is an ortholog of C. elegans
tra-2. In C. elegans,
tra-2 is involved in developmental process involved in reproduction and oocyte fate determination.
laf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA strand annealing activity; identical protein binding activity; and molecular condensate scaffold activity. Involved in several processes, including masculinization of hermaphroditic germ-line; positive regulation of embryonic development; and positive regulation of fertilization. Located in P granule. Expressed in germ line. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and syndromic X-linked intellectual disability. Is an ortholog of human DDX3X (DEAD-box helicase 3 X-linked) and DDX3Y (DEAD-box helicase 3 Y-linked).
Cre-tra-4 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: Zinc finger C2H2 superfamily and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-4. In C. elegans,
tra-4 is involved in hermaphrodite somatic sex determination; negative regulation of vulval development; and regulation of gene expression.
OVOC11374 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Is predicted to encode a protein with the following domains: Zinc finger C2H2 superfamily and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-4. In C. elegans,
tra-4 is involved in hermaphrodite somatic sex determination; negative regulation of vulval development; and regulation of gene expression.
Cbn-tra-4 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Zinc finger C2H2 superfamily and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-4. In C. elegans,
tra-4 is involved in hermaphrodite somatic sex determination; negative regulation of vulval development; and regulation of gene expression.
Cbr-tra-4 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Is predicted to encode a protein with the following domains: Zinc finger C2H2 superfamily and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-4. In C. elegans,
tra-4 is involved in hermaphrodite somatic sex determination; negative regulation of vulval development; and regulation of gene expression.
Cjp-tra-4 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Is predicted to encode a protein with the following domains: Zinc finger C2H2 superfamily and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-4. In C. elegans,
tra-4 is involved in hermaphrodite somatic sex determination; negative regulation of vulval development; and regulation of gene expression.
mpk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables MAP kinase activity. Involved in several processes, including determination of adult lifespan; intracellular signal transduction; and positive regulation of nitrogen compound metabolic process. Located in cytoplasm and nucleus. Expressed in F cell; U cell; germ line; gonad; and oocyte. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Noonan syndrome 13; carcinoma (multiple); and childhood pilocytic astrocytoma. Is an ortholog of human MAPK1 (mitogen-activated protein kinase 1).
SRAE_2000228700 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-4. In C. elegans,
tra-4 is involved in hermaphrodite somatic sex determination; negative regulation of vulval development; and regulation of gene expression.
Ppa-tra-4 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans
tra-4. In C. elegans,
tra-4 is involved in hermaphrodite somatic sex determination; negative regulation of vulval development; and regulation of gene expression.
pps [Search on AGR]
Drosophila melanogaster protein partner of snf (pps) encodes a protein that is part of the machinery required for sex-specific splicing of the Sxl and tra pre-mRNAs.
clp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Involved in several processes, including cellular response to calcium ion; muscle cell cellular homeostasis; and positive regulation of sarcomere organization. Located in M band. Expressed in GABAergic neurons; hypodermis; intestine; pharyngeal muscle cell; and vulva. Used to study Duchenne muscular dystrophy and hereditary spastic paraplegia. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; hereditary spastic paraplegia 76; and stomach cancer. Is an ortholog of human CAPN3 (calpain 3) and CAPN9 (calpain 9).
cul-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase binding activity. Involved in several processes, including anaphase-promoting complex-dependent catabolic process; positive regulation of metaphase/anaphase transition of meiotic cell cycle; and reproductive process. Located in cytoplasm and nucleus. Part of Cul2-RING ubiquitin ligase complex. Expressed in several structures, including P1; P12; P2; germ line; and nerve ring. Is an ortholog of human CUL2 (cullin 2).
fkh-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables sequence-specific DNA binding activity. Involved in male germ-line sex determination and male gonad development. Predicted to be located in nucleus. Expressed in gonadal sheath cell; male gonad; somatic gonad precursor; spermatheca; and in male. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 4. Is an ortholog of human FOXI2 (forkhead box I2) and FOXI3 (forkhead box I3).
Ly39 [Search on AGR]
Mus musculus PHENOTYPE: This locus controls an antigen strongly expressed on B lymphoblasts. High expression of Ly39.1 is seen in DBA/2, DBA/1, AKR/J, B10.D2/n, NZB, MRL and BXSB strains. Low to no expression is seen in C57BL/10, C57BL/6, C57L, A, BALB/c, CAL-20 and CB-20. [provided by MGI curators]
ref-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including neuron fate specification; positive regulation of transcription by RNA polymerase II; and regulation of cell division. Acts upstream of or within with a positive effect on nematode larval development. Located in nucleus. Expressed in several structures, including IL1 neuron; P3.p male; neuroblasts; rectal epithelial cell; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including Dandy-Walker syndrome; X-linked VACTERL association; and holoprosencephaly 5. Is an ortholog of several human genes including ZIC1 (Zic family member 1); ZIC2 (Zic family member 2); and ZIC3 (Zic family member 3).
ify-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protease binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including cortical granule exocytosis; nuclear division; and protein stabilization. Located in condensed chromosome; cytoplasm; and spindle microtubule. Expressed in germ cell.
T04F3.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transaminase activity. Predicted to be involved in amino acid metabolic process. Is an ortholog of human ACCS (1-aminocyclopropane-1-carboxylate synthase homolog (inactive)) and ACCSL (1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like).