utx-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin DNA binding activity; and histone H3K27me2/H3K27me3 demethylase activity. Involved in cell fate specification and programmed cell death. Part of MLL3/4 complex. Expressed in several structures, including germ line; gonad; intestine; pharynx; and tail. Human ortholog(s) of this gene implicated in several diseases, including Kabuki syndrome; breast cancer (multiple); and carcinoma (multiple). Is an ortholog of human KDM6A (lysine demethylase 6A) and UTY (ubiquitously transcribed tetratricopeptide repeat containing, Y-linked).