pink-1

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including axon extension involved in axon guidance; cellular response to oxidative stress; and positive regulation of protein ubiquitination. Located in mitochondrion. Expressed in hermaphrodite distal tip cell; intestine; neurons; pharynx; and vulva. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease 6. Is an ortholog of human PINK1 (PTEN induced kinase 1).