Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; procyanidin; and Sodium Chloride based on RNA-seq and microarray studies.
Is affected by several genes including daf-12; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Cadmium Chloride; bortezomib; and resveratrol based on RNA-seq and microarray studies.
Enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity and glycoprotein 3-alpha-L-fucosyltransferase activity. Involved in carbohydrate biosynthetic process and fucosylation. Predicted to be located in Golgi membrane. Expressed in chemosensory neurons; pharyngeal-intestinal valve; rectal valve cell; and retrovesicular ganglion. Is an ortholog of human FUT3 (fucosyltransferase 3 (Lewis blood group)); FUT5 (fucosyltransferase 5); and FUT6 (fucosyltransferase 6).
PHENOTYPE: Mice homozygous for an endonuclease-mediated allele exhibit complete embryonic lethality during organogenesis with evidence of heart failure. [provided by MGI curators]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased cell proliferation of urothelial cells without histological evidence of hyperplasia. [provided by MGI curators]
PHENOTYPE: Though inactivation of this gene results in apoptotic abnormalities, homozygous null mice develop normally and show no evidence of tumorigenesis. [provided by MGI curators]