crld-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable calcium ion binding activity and protein disulfide isomerase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum lumen and endoplasmic reticulum membrane. Expressed in several structures, including body wall musculature; gonad; hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in atrioventricular septal defect. Is an ortholog of human CRELD1 (cysteine rich with EGF like domains 1) and CRELD2 (cysteine rich with EGF like domains 2).